twoPhaseGAS - Two-Phase Genetic Association Study design and analysis with
missing covariates by design
Provides functionality for selecting and analyzing
individuals in two-phase genetic association studies. Phase 1
data usually come from GWAS results and we assume phase 2
genetic data will be part of a targeted genome sequencing /
fine-mapping study. The package assists in selecting a subset
of individuals that will be sequenced for phase 2. Once phase 2
data have been collected, the package implements methods to
analyze phase 1 and 2 data together using semi-parametric
regression models.