Package: twoPhaseGAS
Type: Package
Title: Two-Phase Genetic Association Study design and analysis with
        missing covariates by design
Version: 1.08
Date: 2021-11-01
Author: Osvaldo Espin-Garcia <osvaldo.espingarcia@utoronto.ca>,
        Apostolos Dimitromanolakis <apostolis@live.ca>, Shelley Bull
        <bull@lunenfeld.ca>
Maintainer: Osvaldo Espin-Garcia <osvaldo.espingarcia@utoronto.ca>
Description: Provides functionality for selecting and analyzing
        individuals in two-phase genetic association studies. Phase 1
        data usually come from GWAS results and we assume phase 2
        genetic data will be part of a targeted genome sequencing /
        fine-mapping study. The package assists in selecting a subset
        of individuals that will be sequenced for phase 2. Once phase 2
        data have been collected, the package implements methods to
        analyze phase 1 and 2 data together using semi-parametric
        regression models.
License: GPL (>= 2)
Depends: R (>= 2.15.2), stats, MASS, data.table, Matrix, dfoptim,
        nloptr, enrichwith
VignetteBuilder: knitr
RoxygenNote: 7.2.1
Suggests: knitr, testthat, rmarkdown, gplots
Encoding: UTF-8
Config/pak/sysreqs: cmake
Repository: https://egosv.r-universe.dev
Date/Publication: 2022-11-06 21:52:59 UTC
RemoteUrl: https://github.com/egosv/twophasegas
RemoteRef: HEAD
RemoteSha: ef0e7b971aa3e6d198de8592b27d77be10bc9fab
NeedsCompilation: no
Packaged: 2026-10-31 09:56:00 UTC; root